Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968931 | 0.82 | ACHE (0.47) | ACHEBCHECCR3KDM4EATM | |
| SCHEMBL8969391 | 0.82 | ACHE (0.47) | ACHEBCHECCR3KDM4EATM | |
| SCHEMBL7685732 | 0.78 | USP2 (0.44) | ACHEBCHEMEN1TSHRKMT2A | |
| SCHEMBL28915706 | 0.78 | USP2 (0.44) | ACHEBCHEMEN1TSHRKMT2A | |
| SCHEMBL28583632 | 0.71 | KDM4E (0.42) | ACHEBCHEKDM4EATMHSD17B10 | |
| SCHEMBL8969328 | 0.70 | CCR3 (0.38) | ACHEBCHECCR3KDM4EMAPK1 | |
| SCHEMBL30842142 | 0.69 | TAAR1 (0.44) | TSHRUSP2MAPTHTT | |
| SCHEMBL3385589 | 0.67 | ACHE (0.67) | ACHEBCHEKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL8970098 | 0.67 | CCR3 (0.37) | ACHEBCHECCR3KDM4EATM | |
| SCHEMBL9541773 | 0.66 | MEN1 (0.66) | ACHEBCHEKDM4EHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |