Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | CFTR | P13569 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.67 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541773 | 0.95 | MEN1 (0.66) | ACHEKDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL9387899 | 0.94 | MEN1 (0.68) | ACHEKDM4EALDH1A1HSD17B10USP2 | |
| Deoxyvasicinone SCHEMBL864139 | 0.80 | ALDH1A1 (1.00) | ACHEKDM4EALDH1A1HSD17B10USP2 | |
| Deoxyvasicinone SCHEMBL29359475 | 0.80 | ALDH1A1 (1.00) | ACHEKDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL8969079 | 0.78 | ACHE (0.89) | ACHEKDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL29618881 | 0.75 | MEN1 (0.97) | ACHEKDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL5511965 | 0.75 | MEN1 (0.97) | ACHEKDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL503163 | 0.75 | ALDH1A1 (0.60) | ACHEKDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL8969257 | 0.75 | POLB (0.50) | ACHEKDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL6288230 | 0.74 | MEN1 (1.00) | ACHEKDM4EALDH1A1HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594873-B1 | PYRROLIDINOHYDROCHINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2010-12-15 | — | — | EP | disclosed |
| US-7214703-B2 | Compounds for modulators of chemokine activity | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-08 | — | — | US | disclosed |
| EP-1594873-A1 | PYRROLIDINOHYDROCHINAZOLINES | Boehringer Ingelheim International GmbH (DE) | 2005-11-16 | — | — | EP | disclosed |
| US-20050027122-A1 | Compounds for modulators of chemokine activity | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-02-03 | — | — | US | disclosed |
| WO-2004072074-A1 | PYRROLIDINOHYDROCHINAZOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050027122-A1 | Compounds for modulators of chemokine activity | CXCR2, CCL2, CXCR1 | ACHE 2548/4885KDM4E 4846/4885ALDH1A1 604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.