Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 8/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969453 | 0.85 | ACHE (0.45) | ACHEPARP1BCHEOPRL1OGFRL1 | |
| SCHEMBL8968188 | 0.85 | ACHE (0.32) | ACHEOPRL1OGFRL1 | |
| SCHEMBL8970053 | 0.85 | ACHE (0.38) | ACHEPARP1BCHEGRIN1GRIN2A | |
| SCHEMBL8969096 | 0.82 | XPO1 (0.36) | HRH4ACHE | |
| SCHEMBL8968721 | 0.78 | KDM4E (0.38) | HRH4ELANEPARP1 | |
| SCHEMBL8968293 | 0.77 | — | — | |
| SCHEMBL8968897 | 0.75 | BCHE (0.31) | ACHEBCHE | |
| SCHEMBL8969661 | 0.73 | BCHE (0.34) | HRH4ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL8969894 | 0.73 | KDM4E (0.38) | HRH4ELANEACHEBCHEGRIN1 | |
| SCHEMBL8969011 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |