Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.30 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969422 | 0.85 | HRH4 (0.34) | ACHEBCHEPARP1OPRL1OGFRL1 | |
| SCHEMBL8968188 | 0.84 | ACHE (0.32) | ACHEOPRL1OGFRL1 | |
| SCHEMBL8970053 | 0.84 | ACHE (0.38) | ACHEBCHEPARP1PIK3CDPIK3CG | |
| SCHEMBL8969096 | 0.84 | XPO1 (0.36) | ACHEHRH3CHRNB2CHRNA4 | |
| SCHEMBL8969437 | 0.82 | BCHE (0.35) | ACHEBCHE | |
| SCHEMBL8968293 | 0.76 | — | — | |
| SCHEMBL8968356 | 0.74 | — | — | |
| SCHEMBL8970437 | 0.74 | MPO (0.36) | ACHEBCHECYP11B2 | |
| SCHEMBL8968897 | 0.74 | BCHE (0.31) | ACHEBCHE | |
| SCHEMBL8969011 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |