Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969117 | 0.99 | ACHE (0.71) | ACHESMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL8968576 | 0.89 | SMN1; SMN2 (0.69) | ACHESMN1; SMN2ALDH1A1RAB9ATP53 | |
| SCHEMBL8968338 | 0.87 | SMN1; SMN2 (0.71) | ACHESMN1; SMN2ALDH1A1RAB9ATP53 | |
| SCHEMBL8968733 | 0.83 | ACHE (0.97) | ACHESMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL8969364 | 0.83 | ACHE (0.69) | ACHESMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL8969578 | 0.82 | ACHE (0.71) | ACHESMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL8969432 | 0.82 | ACHE (0.71) | ACHESMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL8968942 | 0.82 | ALDH1A1 (0.80) | ACHESMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL8968366 | 0.82 | ACHE (1.00) | ACHESMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL8968695 | 0.82 | SMN1; SMN2 (0.60) | ACHESMN1; SMN2ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |