Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 7/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772617 | 0.74 | ALDH1A1 (0.46) | MMP13L3MBTL1LMNA | |
| SCHEMBL8968633 | 0.72 | CHRM2 (0.39) | MMP13FDFT1MMP2 | |
| SCHEMBL8707627 | 0.71 | HRH3 (0.42) | LMNA | |
| SCHEMBL9187873 | 0.71 | FDFT1 (0.43) | MMP13FDFT1MMP2MAPTLMNA | |
| SCHEMBL8592551 | 0.71 | FDFT1 (0.43) | MMP13FDFT1MMP2MAPTLMNA | |
| SCHEMBL8968689 | 0.70 | CHRM2 (0.39) | MMP13FDFT1MMP2 | |
| SCHEMBL8706049 | 0.69 | MMP13 (0.36) | MMP13 | |
| SCHEMBL8969019 | 0.68 | LTA4H (0.42) | MMP13FDFT1MMP2LMNA | |
| Hydrochloric Acid SCHEMBL8418615 | 0.66 | FDFT1 (0.37) | MMP13FDFT1MMP2 | |
| SCHEMBL21049648 | 0.66 | CYP2C19 (0.49) | POLBLMNAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |