Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969445 | 1.00 | HTR2A (0.36) | HTR2AHTR2CKLK7NOS1NOS2 | |
| SCHEMBL8969696 | 0.80 | CTSD (0.32) | — | |
| SCHEMBL8969702 | 0.80 | CTSD (0.32) | — | |
| SCHEMBL8969931 | 0.76 | CTSD (0.50) | HTR2AHTR2C | |
| SCHEMBL8969936 | 0.76 | CTSD (0.50) | HTR2AHTR2C | |
| SCHEMBL8968664 | 0.76 | KLK7 (0.32) | HTR2AHTR2CKLK7NOS1NOS2 | |
| SCHEMBL8969208 | 0.73 | KLK7 (0.32) | HTR2AHTR2CKLK7 | |
| SCHEMBL8968500 | 0.71 | NOS1 (0.35) | KLK7NOS1NOS2 | |
| SCHEMBL8969502 | 0.65 | KLK7 (0.32) | KLK7 | |
| SCHEMBL8969039 | 0.63 | OPRM1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |