Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508368 | 0.87 | POLB (0.50) | POLBLMNAHSD17B10MAPTBCHE | |
| SCHEMBL28209564 | 0.83 | AKR1C3 (0.47) | LMNAHSD17B10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10949570 | 0.81 | ALDH1A1 (0.47) | LMNAMAPTALDH1A1TSHR | |
| SCHEMBL10943238 | 0.81 | ALDH1A1 (0.47) | LMNAMAPTALDH1A1TSHR | |
| SCHEMBL10944016 | 0.81 | ALDH1A1 (0.47) | LMNAMAPTALDH1A1TSHR | |
| SCHEMBL10942047 | 0.81 | ALDH1A1 (0.47) | LMNAMAPTALDH1A1TSHR | |
| SCHEMBL28872151 | 0.80 | USP2 (0.43) | POLBLMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL15877038 | 0.79 | LMNA (0.38) | POLBLMNAHSD17B10MAPTBCHE | |
| SCHEMBL4071095 | 0.78 | TSHR (0.57) | POLBLMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL4062734 | 0.78 | LMNA (0.41) | POLBLMNAHSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209355-A1 | NUCLEIC ACID BINDING PROTEIN FORMULATIONS AND USES THEREOF | SPOTLIGHT THERAPEUTICS | 2024-06-27 | — | — | US | disclosed |
| WO-2022140795-A2 | NUCLEIC ACID BINDING PROTEIN FORMULATIONS AND USES THEREOF | SPOTLIGHT THERAPEUTICS (US) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022056231-A1 | COMPOSITIONS AND METHODS FOR SCREENING CELL INTERNALIZING AGENTS | SPOTLIGHT THERAPEUTICS (US) | 2022-03-17 | — | — | WO | disclosed |
| CN-114040775-A | Targeted active gene editing agents and methods of use | 光点治疗公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-114026123-A | Targeted active gene editing agents and methods of use | 光点治疗公司 | 2022-02-08 | — | — | CN | disclosed |
| EP-3941943-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | Spotlight Therapeutics (US) | 2022-01-26 | — | — | EP | disclosed |
| EP-3941515-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | Spotlight Therapeutics (US) | 2022-01-26 | — | — | EP | disclosed |
| US-20220010337-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | SPOTLIGHT THERAPEUTICS (US) | 2022-01-13 | — | — | US | disclosed |
| US-20220002695-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | SPOTLIGHT THERAPEUTICS (US) | 2022-01-06 | — | — | US | disclosed |
| WO-2021062201-A1 | COMPOSITIONS AND METHODS FOR NUCLEOPROTEIN TARGETING AND EXPRESSION | SPOTLIGHT THERAPEUTICS (US) | 2021-04-01 | — | — | WO | disclosed |
| WO-2020198151-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | SPOTLIGHT THERAPEUTICS (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2020198160-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | SPOTLIGHT THERAPEUTICS (US) | 2020-10-01 | — | — | WO | disclosed |
| EP-0699209-A1 | PROCESSES AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994026779-A1 | PROCESSES AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |