Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.40 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418566 | 0.94 | FDFT1 (0.45) | CYP4Z1FDFT1MAPK1L3MBTL1ALOX5 | |
| SCHEMBL8419852 | 0.90 | PPARA (0.40) | L3MBTL1ALOX5PPARATDP1ALDH1A1 | |
| SCHEMBL8969386 | 0.87 | PPARA (0.46) | MAPK1ALOX5PPARAAKR1C3AKR1C2 | |
| SCHEMBL8419978 | 0.87 | PPARA (0.42) | ALOX5PPARAALDH1A1LMNA | |
| SCHEMBL8421859 | 0.86 | PPARA (0.41) | ALOX5PPARAALDH1A1LMNA | |
| SCHEMBL27460107 | 0.85 | APP (0.44) | FDFT1MAPK1L3MBTL1ALOX5PPARA | |
| SCHEMBL9432238 | 0.84 | PPARA (0.47) | ALOX5PPARA | |
| SCHEMBL8419729 | 0.84 | PPARA (0.39) | FDFT1ALOX5PPARATDP1AKR1C3 | |
| SCHEMBL8419836 | 0.83 | ALOX5 (0.41) | L3MBTL1ALOX5PPARATDP1AKR1C3 | |
| SCHEMBL8417976 | 0.83 | PPARA (0.42) | ALOX5PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |