Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564397 | 0.88 | SLC6A3 (0.38) | SLC6A3SSTR3MEN1KMT2AOPRK1 | |
| SCHEMBL4631283 | 0.84 | SSTR3 (0.39) | SLC6A3SSTR3MEN1KMT2AOPRK1 | |
| SCHEMBL7750432 | 0.82 | SCN1A (0.38) | SLC6A3SSTR3MEN1KMT2ATDP1 | |
| SCHEMBL7768729 | 0.81 | MEN1 (0.40) | SLC6A3SSTR3MEN1KMT2ANPC1 | |
| SCHEMBL7426709 | 0.80 | MEN1 (0.43) | SLC6A3SSTR3MEN1KMT2ANPC1 | |
| SCHEMBL7765726 | 0.78 | MEN1 (0.41) | SLC6A3SSTR3MEN1KMT2AOPRK1 | |
| SCHEMBL7765828 | 0.78 | MEN1 (0.41) | SLC6A3SSTR3MEN1KMT2ANPC1 | |
| SCHEMBL8124689 | 0.78 | MEN1 (0.43) | SLC6A3SSTR3MEN1KMT2ANPC1 | |
| SCHEMBL7958095 | 0.77 | MEN1 (0.44) | SLC6A3SSTR3MEN1KMT2ANPC1 | |
| SCHEMBL7847786 | 0.73 | MEN1 (0.42) | SLC6A3SSTR3MEN1KMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700386-A1 | NEUROKININ RECEPTOR ANTAGONISTS | SANOFI (FR) | 1996-03-13 | — | — | EP | disclosed |
| WO-1995026338-A1 | NEUROKININ RECEPTOR ANTAGONISTS | SANOFI (FR) | 1995-10-05 | — | — | WO | disclosed |