Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426709 | 0.83 | MEN1 (0.43) | MEN1KMT2AKCNA5SCN5AKDM4C | |
| SCHEMBL8124689 | 0.81 | MEN1 (0.43) | MEN1KMT2AKCNA5SCN5AKDM4C | |
| SCHEMBL7768729 | 0.79 | MEN1 (0.40) | MEN1KMT2AKCNA5SCN5AKDM4C | |
| SCHEMBL7958095 | 0.78 | MEN1 (0.44) | MEN1KMT2AKCNA5SCN5AKDM4C | |
| SCHEMBL7765828 | 0.77 | MEN1 (0.41) | MEN1KMT2AKCNA5SCN5AKDM4C | |
| SCHEMBL8556420 | 0.74 | MEN1 (0.41) | MEN1KMT2AKCNA5SCN5ACHEK1 | |
| SCHEMBL8125379 | 0.74 | MEN1 (0.44) | MEN1KMT2AKCNA5SCN5AKDM4C | |
| SCHEMBL7765726 | 0.74 | MEN1 (0.41) | MEN1KMT2AKCNA5SCN5AKDM4C | |
| SCHEMBL8703966 | 0.73 | MEN1 (0.43) | MEN1KMT2AKCNA5SCN5AKDM4C | |
| SCHEMBL8969658 | 0.73 | SLC6A3 (0.36) | MEN1KMT2ASLC6A3SSTR3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003743-A4 | 3,3-DISUBSTITUTED PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | disclosed |
| US-6124319-A | TREATING INFLAMMATORY AND IMMUNOREGULATORY DISORDERS AND DISEASES, INCLUDING ASTHMA AND ALLERGIC DISEASES, AUTOIMMUNE PATHOLOGIES SUCH AS RHEUMATOID ARTHRITIS AND ATHEROSCLEROSIS | MERCK & CO., INC. (US) | 2000-09-26 | — | — | US | disclosed |
| EP-1003743-A1 | 3,3-DISUBSTITUTED PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1998031364-A1 | 3,3-DISUBSTITUTED PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 1998-07-23 | — | — | WO | disclosed |