Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968349 | 0.89 | ACHE (0.53) | ACHEDRD2DRD4DRD3BCHE | |
| SCHEMBL8969749 | 0.85 | ACHE (0.60) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969711 | 0.83 | ACHE (0.43) | ACHEDRD2DRD4DRD3BCHE | |
| SCHEMBL8969091 | 0.77 | ACHE (0.60) | ACHEDRD4BCHEMEN1USP2 | |
| SCHEMBL8969190 | 0.76 | ACHE (0.89) | ACHEDRD2DRD4DRD3BCHE | |
| SCHEMBL8968773 | 0.75 | ACHE (0.97) | ACHEDRD2DRD4DRD3BCHE | |
| SCHEMBL8968453 | 0.74 | ACHE (1.00) | ACHEDRD2DRD4DRD3BCHE | |
| SCHEMBL8969789 | 0.74 | ACHE (0.46) | ACHEDRD2DRD4DRD3BCHE | |
| SCHEMBL8969632 | 0.73 | ACHE (0.40) | ACHEDRD2DRD4DRD3BCHE | |
| SCHEMBL8969927 | 0.73 | ACHE (0.54) | ACHEDRD4BCHEMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |