Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968341 | 0.99 | ACHE (0.53) | ACHEBCHEALDH1A1CYP3A4MEN1 | |
| SCHEMBL8968561 | 0.82 | ACHE (0.63) | ACHEBCHEALDH1A1CYP3A4MEN1 | |
| SCHEMBL8970082 | 0.80 | ACHE (0.50) | ACHEBCHEALDH1A1CYP3A4MEN1 | |
| SCHEMBL8969676 | 0.77 | ACHE (0.50) | ACHEBCHEALDH1A1CYP3A4MEN1 | |
| SCHEMBL8970605 | 0.76 | ACHE (0.55) | ACHEBCHEALDH1A1CYP3A4MEN1 | |
| SCHEMBL8968431 | 0.76 | ACHE (0.45) | ACHEBCHEALDH1A1CYP3A4MEN1 | |
| SCHEMBL8968295 | 0.75 | ACHE (0.47) | ACHEBCHEALDH1A1CYP3A4MEN1 | |
| SCHEMBL8968930 | 0.74 | ACHE (0.47) | ACHEALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL8968742 | 0.74 | ACHE (0.56) | ACHEBCHEALDH1A1CYP3A4MEN1 | |
| SCHEMBL8969588 | 0.73 | ACHE (0.55) | ACHEBCHEALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |