Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968671 | 0.90 | MEN1 (0.62) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8969578 | 0.83 | ACHE (0.71) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8969117 | 0.80 | ACHE (0.71) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8969432 | 0.80 | ACHE (0.71) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8968366 | 0.80 | ACHE (1.00) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8968638 | 0.79 | ACHE (0.69) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8969364 | 0.79 | ACHE (0.69) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8968733 | 0.79 | ACHE (0.97) | ACHEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9387899 | 0.76 | MEN1 (0.68) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL9541773 | 0.75 | MEN1 (0.66) | ACHEMEN1KMT2AHDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |