SCHEMBL8969933

SCHEMBL8969933

Fc1cccc2c1CN1C(=N2)C2C=CC1C2

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.32
CTSD P07339 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8968716 0.83 CTSD (0.46) CTSD
SCHEMBL8968445 0.78
SCHEMBL8969954 0.72 EGFR (0.34)
SCHEMBL8969063 0.71 CHRNB2 (0.36) MAPK1CTSD
SCHEMBL8969030 0.69
SCHEMBL8969988 0.68 CHRNB2 (0.35)
SCHEMBL8969224 0.67 CTSD (0.30) CTSD
SCHEMBL8969474 0.67 CTSD (0.30) CTSD
SCHEMBL8969582 0.64
SCHEMBL8970272 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486512-A LEARNING ENHANCEMENT WARNER-LAMBERT COMPANY (US) 1996-01-23 US disclosed
WO-1993003034-A1 QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS WARNER-LAMBERT COMPANY (US) 1993-02-18 WO disclosed