Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968332 | 0.83 | ACHE (0.30) | ACHE | |
| SCHEMBL8968640 | 0.77 | ACHE (0.30) | ACHEGRM1 | |
| SCHEMBL8968819 | 0.71 | MAPK1 (0.34) | CHRNB2CHRNA7CHRNA4ACHE | |
| SCHEMBL8968722 | 0.66 | ACHE (0.30) | ACHE | |
| SCHEMBL8969540 | 0.66 | BCHE (0.32) | ACHE | |
| SCHEMBL8968877 | 0.66 | PDE3B (0.33) | ACHE | |
| SCHEMBL8969710 | 0.64 | HTR2C (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL8968436 | 0.64 | ACHE (0.70) | ACHE | |
| SCHEMBL28374074 | 0.63 | CTSD (0.38) | — | |
| SCHEMBL8968432 | 0.61 | CTSD (0.48) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |