⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464053 | 0.75 | — | — | |
| SCHEMBL2761274 | 0.71 | LMNA (0.30) | — | |
| SCHEMBL8773279 | 0.71 | — | — | |
| SCHEMBL10939461 | 0.71 | — | — | |
| SCHEMBL22449362 | 0.71 | — | — | |
| SCHEMBL395923 | 0.69 | — | — | |
| SCHEMBL8773278 | 0.69 | — | — | |
| SCHEMBL10913195 | 0.68 | TSHR (0.38) | — | |
| SCHEMBL10616524 | 0.67 | — | — | |
| SCHEMBL10935873 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8617395-B2 | Thin film composite membranes and their method of preparation and use | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2013-12-31 | — | — | US | claimed |
| WO-2012050730-A2 | THIN FILM COMPOSITE MEMBRANES AND THEIR METHOD OF PREPARATION AND USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2012-04-19 | — | — | WO | claimed |
| US-20120080147-A1 | THIN FILM COMPOSITE MEMBRANES AND THEIR METHOD OF PREPARATION AND USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2012-04-05 | — | — | US | claimed |
| JP-5139931-A | — | — | None | — | — | JP | disclosed |
| US-8153726-B2 | Highly oxygen permeable rigid contact lenses from polyacetylenes | THE LAGADO CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-20070078245-A1 | Highly Oxygen Permeable Rigid Contact Lenses from Polyacetylenes | THE LAGADO CORPORATION (US) | 2007-04-05 | — | — | US | disclosed |
| JP-H05139931-A | MANICURE | SHIN ETSU CHEM CO LTD | 1993-06-08 | — | — | JP | disclosed |
| US-5176724-A | Polyethersulfone porous support, ultrathin acetylenic polymer film, and interface layer | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| US-5162562-A | Preparation of metallated and substituted alkynes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-11-10 | — | — | US | disclosed |
| US-5149751-A | PROCESS FOR THE PREPARATION OF 1-MONOALKYL-DIMETHYLSILYLPROPYNE POLYMERS | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| US-5062998-A | Preparation of metallated and substituted alkynes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-11-05 | — | — | US | disclosed |
| EP-0358457-A2 | Process for the preparation of 1-monoalkyldimethylsilyl-propyne polymers | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-03-14 | — | — | EP | disclosed |
| US-4778868-A | SILANE-SUBSTITUTED ACETYLENIC HOMOPOLYMERS; WORKABILITY | TOSHINOBU HIGASHIMURA (JP) | 1988-10-18 | — | — | US | disclosed |
| US-4755193-A | Separating gas mixture using permselective unsaturated silane-containing polymer membrane | Higashimura, Toshinobu (JP) | 1988-07-05 | — | — | US | disclosed |