SCHEMBL8970010

SCHEMBL8970010

CCCCc1nc(C)c(C(=S)OCC)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCC)cc1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 2/20 0.60
AGTR1 P30556 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8902745 0.95 AGTR1 (0.57) AGTR2AGTR1
SCHEMBL8969870 0.95 AGTR2 (0.58) AGTR2
SCHEMBL8970663 0.93 AGTR2 (0.55) AGTR2AGTR1
SCHEMBL8903177 0.92 AGTR1 (0.53) AGTR2AGTR1
SCHEMBL8898998 0.91 AGTR2 (0.69) AGTR2AGTR1
SCHEMBL8902817 0.89 AGTR1 (0.59) AGTR2AGTR1
SCHEMBL8971097 0.88 AGTR2 (0.60) AGTR2AGTR1
SCHEMBL8971357 0.88 AGTR2 (0.58) AGTR2AGTR1
SCHEMBL8969977 0.88 AGTR1 (0.54) AGTR2AGTR1
SCHEMBL8971011 0.86 AGTR2 (0.57) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5482957-A Azole derivatives, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-09 US disclosed