SCHEMBL8971011

SCHEMBL8971011

C=CCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc(C)c2C(O)=S)cc1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 3/20 0.57
AGTR1 P30556 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970663 0.93 AGTR2 (0.55) AGTR2AGTR1
SCHEMBL8971097 0.90 AGTR2 (0.60) AGTR2AGTR1
SCHEMBL8902817 0.88 AGTR1 (0.59) AGTR2AGTR1
SCHEMBL8970714 0.87 AGTR2 (0.62) AGTR2AGTR1
SCHEMBL8902412 0.86 AGTR1 (0.59) AGTR2AGTR1
SCHEMBL8970010 0.86 AGTR2 (0.60) AGTR2AGTR1
SCHEMBL8555500 0.86 AGTR1 (0.75) AGTR2AGTR1
SCHEMBL8901773 0.86 AGTR1 (0.59) AGTR2AGTR1
SCHEMBL8903314 0.85 AGTR2 (0.62) AGTR2AGTR1
SCHEMBL8970656 0.85 AGTR1 (0.65) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5482957-A Azole derivatives, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-09 US disclosed