SCHEMBL8970081

SCHEMBL8970081

CCCOC(=O)C1CSCC1O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.38
PTPN1 P18031 1/20 0.38
PPP1CC P36873 1/20 0.38
HCAR2 Q8TDS4 1/20 0.32
ALDH1A1 P00352 3/20 0.31
USP2 O75604 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970990 0.90 ALDH1A1 (0.41) HCAR2ALDH1A1LMNA
SCHEMBL8970001 0.87 NAAA (0.43) HCAR2ALDH1A1NPSR1LMNA
SCHEMBL8970029 0.87 NAAA (0.43) HCAR2ALDH1A1NPSR1LMNA
SCHEMBL8969051 0.87 NAAA (0.43) HCAR2ALDH1A1NPSR1LMNA
SCHEMBL8969010 0.87 NAAA (0.43) HCAR2ALDH1A1NPSR1LMNA
SCHEMBL8969473 0.87 NAAA (0.43) HCAR2ALDH1A1NPSR1LMNA
SCHEMBL8970421 0.85 CYP1A2 (0.36) PPM1BPTPN1PPP1CCALDH1A1LMNA
SCHEMBL8970499 0.82 PPM1B (0.45) PPM1BPTPN1PPP1CCHCAR2ALDH1A1
SCHEMBL8969484 0.81 ALOX15 (0.33)
SCHEMBL8970171 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376294-B1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI LTD (JP) 1996-03-13 EP disclosed
US-5370821-A Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5269965-A Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES (JP) 1993-12-14 US disclosed
EP-0376294-A1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1990-07-04 EP disclosed