Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.63 |
| ▸ | MARS1 | P56192 | 1/20 | 0.62 |
| ▸ | TARS1 | P26639 | 2/20 | 0.57 |
| ▸ | IARS1 | P41252 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.55 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.55 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.55 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.55 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.55 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970144 | 1.00 | NT5E (0.63) | NT5EMARS1TARS1IARS1ABCB1 | |
| SCHEMBL7757016 | 0.92 | MARS1 (0.73) | MARS1TARS1IARS1ADORA1DNPH1 | |
| SCHEMBL8970328 | 0.85 | NT5E (0.65) | NT5EMARS1ABCB1ADORA1DNPH1 | |
| SCHEMBL8970318 | 0.85 | NT5E (0.65) | NT5EMARS1ABCB1ADORA1DNPH1 | |
| SCHEMBL381959 | 0.83 | NT5E (0.69) | NT5EADORA1DNPH1PRKAB2TRPM2 | |
| SCHEMBL21999782 | 0.83 | NT5E (0.69) | NT5EADORA1DNPH1PRKAB2TRPM2 | |
| SCHEMBL19959560 | 0.83 | NT5E (0.62) | NT5EMARS1ADORA1DNPH1PRKAB2 | |
| SCHEMBL8970435 | 0.83 | NT5E (0.62) | NT5EMARS1ABCB1AHCYPRKACA | |
| SCHEMBL2761284 | 0.83 | MARS1 (0.74) | NT5EMARS1TARS1ADORA1DNPH1 | |
| SCHEMBL24026262 | 0.82 | NT5E (0.75) | NT5EADORA1DNPH1PRKAB2TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417999-B1 | Antiviral compounds | WELLCOME FOUND (GB) | 1996-03-13 | — | — | EP | disclosed |
| EP-0671410-A1 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-09-13 | — | — | EP | disclosed |
| EP-0417999-A1 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-03-20 | — | — | EP | disclosed |