Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969072 | 0.89 | OPRM1 (0.36) | — | |
| SCHEMBL8969608 | 0.89 | OPRM1 (0.33) | — | |
| SCHEMBL8968760 | 0.80 | PDE3B (0.34) | HTR2CHTR2BHTR2A | |
| SCHEMBL8969496 | 0.80 | HTR2C (0.36) | HTR2CHTR2BHTR2A | |
| SCHEMBL8969723 | 0.80 | HTR2C (0.36) | HTR2CHTR2BHTR2A | |
| SCHEMBL8969145 | 0.80 | — | — | |
| SCHEMBL8969508 | 0.78 | PDE3B (0.33) | — | |
| SCHEMBL8969666 | 0.77 | CTSD (0.34) | HTR2CHTR2BHTR2A | |
| SCHEMBL8968350 | 0.75 | — | — | |
| SCHEMBL8969463 | 0.74 | HTR2A (0.33) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |