Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970030 | 0.84 | CTSD (0.50) | CTSDLMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8969774 | 0.82 | HTR2C (0.36) | HTR2CHTR2BCTSDLMNACYP1A2 | |
| SCHEMBL8969270 | 0.81 | — | — | |
| SCHEMBL8969623 | 0.80 | HTR2C (0.36) | HTR2CHTR2BCTSDLMNACYP1A2 | |
| SCHEMBL8970250 | 0.80 | HTR2C (0.32) | HTR2CHTR2BHTR2A | |
| SCHEMBL8968326 | 0.78 | — | — | |
| SCHEMBL8969282 | 0.78 | CTSD (0.34) | HTR2CHTR2BCTSDLMNACYP1A2 | |
| SCHEMBL8969723 | 0.78 | HTR2C (0.36) | HTR2CHTR2BHTR2AOPRL1OPRM1 | |
| SCHEMBL8969608 | 0.76 | OPRM1 (0.33) | OPRL1OPRM1 | |
| SCHEMBL8969903 | 0.75 | PDE3B (0.45) | CTSDLMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |