SCHEMBL8970359

SCHEMBL8970359

CC(C)(C)OC1CSCC1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.36
GRM3 Q14832 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970469 0.78 GRM2 (0.34) GRM2
SCHEMBL8970043 0.78 KMT2A (0.32) GRM2
SCHEMBL31332688 0.75 GRM2 (0.41) GRM2GRM3
SCHEMBL8970231 0.74 KMT2A (0.47)
SCHEMBL8970275 0.73 ALDH1A1 (0.36) GRM2GRM3
SCHEMBL8970065 0.73 GRM2 (0.36) GRM2GRM3
SCHEMBL8969965 0.71
SCHEMBL70312 0.71 GABRR1 (0.43) GRM2GRM3
SCHEMBL15055464 0.71 GABRR1 (0.43) GRM2GRM3
SCHEMBL8970591 0.71 BTK (0.40) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376294-B1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI LTD (JP) 1996-03-13 EP disclosed
US-5370821-A Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5269965-A Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES (JP) 1993-12-14 US disclosed
EP-0376294-A1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1990-07-04 EP disclosed