Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 3/20 | 0.69 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.69 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.69 |
| ▸ | PDE2A | O00408 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | PDE5A | O76074 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122584 | 0.82 | PDE1A (0.63) | PDE1APDE1BPDE1CPDE2AMEN1 | |
| SCHEMBL897036 | 0.82 | PDE1A (1.00) | PDE1APDE1BPDE1CPDE2AMEN1 | |
| SCHEMBL2948025 | 0.81 | PDE1A (0.61) | PDE1APDE1BPDE1CPDE2AMEN1 | |
| SCHEMBL5688395 | 0.80 | PDE2A (0.60) | PDE1APDE1BPDE1CPDE2AMEN1 | |
| SCHEMBL461786 | 0.80 | PDE2A (0.62) | PDE1APDE1BPDE1CPDE2AMEN1 | |
| Verofylline SCHEMBL636856 | 0.79 | PDE1A (0.78) | PDE1APDE1BPDE1CPDE2AMEN1 | |
| SCHEMBL2472008 | 0.79 | PDE1A (0.61) | PDE1APDE1BPDE1CPDE2AMEN1 | |
| Water SCHEMBL28799658 | 0.78 | PDE2A (0.60) | PDE1APDE1BPDE1CPDE2AMEN1 | |
| SCHEMBL18834910 | 0.78 | PDE2A (0.53) | PDE1APDE1BPDE1CPDE2AMEN1 | |
| SCHEMBL5272642 | 0.77 | CYP2C19 (0.48) | PDE1APDE1BPDE1CPDE2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066413-A1 | COMPOSITIONS FOR TREATMENT OF INFLAMMATION | METRO INTERNATIONAL BIOTECH, LLC | 2025-02-27 | — | — | US | disclosed |
| EP-4452279-A1 | COMPOSITIONS FOR TREATMENT OF INFLAMMATION | Metro International Biotech, LLC (US) | 2024-10-30 | — | — | EP | disclosed |
| US-11878994-B1 | Compositions for treatment of inflammation | METRO INTERNATIONAL BIOTECH, LLC (US) | 2024-01-23 | — | — | US | disclosed |
| WO-2023122190-A1 | COMPOSITIONS FOR TREATMENT OF INFLAMMATION | METRO INTERNATIONAL BIOTECH, LLC (US) | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066413-A1 | COMPOSITIONS FOR TREATMENT OF INFLAMMATION | NQO1, NAMPT, MPO | PDE1A 2019/4885PDE1B 2282/4885PDE1C 2592/4885 |
| US-11878994-B1 | Compositions for treatment of inflammation | NQO1, NAMPT, MPO | PDE1A 2019/4885PDE1B 2282/4885PDE1C 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.