Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970621 | 1.00 | ALDH1A1 (0.34) | ALDH1A1TDP1ENPP2PTPN11PTGS1 | |
| SCHEMBL8970616 | 0.93 | PTPN11 (0.34) | PTPN11FPR2S1PR5S1PR1LPAR2 | |
| SCHEMBL8970559 | 0.92 | PTPN11 (0.32) | ALDH1A1TDP1ENPP2PTPN11FPR2 | |
| SCHEMBL8970757 | 0.91 | PTPN11 (0.34) | PTPN11PTGS1PTGS2S1PR1 | |
| SCHEMBL8969882 | 0.87 | CNR2 (0.34) | ENPP2 | |
| SCHEMBL8969591 | 0.87 | CNR2 (0.34) | ENPP2 | |
| SCHEMBL8969780 | 0.87 | CNR2 (0.34) | ENPP2 | |
| SCHEMBL8957200 | 0.86 | FPR2 (0.37) | ALDH1A1TDP1ENPP2PTPN11FPR2 | |
| SCHEMBL8957325 | 0.86 | FPR2 (0.37) | ALDH1A1TDP1ENPP2PTPN11FPR2 | |
| SCHEMBL8957219 | 0.86 | FPR2 (0.37) | ALDH1A1TDP1ENPP2PTPN11FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |