Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.34 |
| ▸ | THRA | P10827 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970738 | 0.91 | S1PR1 (0.34) | PTPN11THRATHRBS1PR1S1PR3 | |
| SCHEMBL8970621 | 0.91 | ALDH1A1 (0.34) | PTPN11S1PR1PTGS1PTGS2 | |
| SCHEMBL8970598 | 0.91 | ALDH1A1 (0.34) | PTPN11S1PR1PTGS1PTGS2 | |
| SCHEMBL8970616 | 0.88 | PTPN11 (0.34) | PTPN11THRATHRBS1PR1S1PR3 | |
| SCHEMBL8972128 | 0.85 | PPARD (0.34) | PTPN11THRATHRBS1PR1S1PR3 | |
| SCHEMBL8969819 | 0.85 | RARB (0.42) | PTPN11THRBS1PR1S1PR3RARB | |
| SCHEMBL8971819 | 0.84 | RARB (0.37) | PTPN11THRATHRBS1PR1S1PR3 | |
| SCHEMBL8953332 | 0.84 | FPR2 (0.36) | PTPN11THRATHRBRARBPPARD | |
| SCHEMBL8953724 | 0.84 | FPR2 (0.36) | PTPN11THRATHRBRARBPPARD | |
| SCHEMBL8953544 | 0.84 | FPR2 (0.36) | PTPN11THRATHRBRARBPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |