SCHEMBL8970877

SCHEMBL8970877

Cl[Si](c1ccccc1)(C1C=Cc2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8369966 0.87 HTR6 (0.33)
SCHEMBL7050222 0.80 GPR3 (0.35)
Hydrochloric Acid SCHEMBL7118144 0.77 CYP19A1 (0.34)
Hydrochloric Acid SCHEMBL7049642 0.77 GPR3 (0.33)
Hydrochloric Acid SCHEMBL7048569 0.77 GPR3 (0.33)
Hydrochloric Acid SCHEMBL7049650 0.77 CYP19A1 (0.34)
Hydrochloric Acid SCHEMBL7056957 0.77 GPR3 (0.33)
Hydrochloric Acid SCHEMBL7048575 0.77 CYP19A1 (0.34)
Hydrochloric Acid SCHEMBL7118139 0.77 GPR3 (0.33)
Hydrochloric Acid SCHEMBL7056966 0.77 CYP19A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5492974-A Process for preparing polymer bound metallocenes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492973-A Polymer bound ligands PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492978-A Process for preparing catalyst system PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492985-A Polymerization processes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492975-A Polymer bound metallocenes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
EP-0690076-A1 Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1996-01-03 EP disclosed
US-5473020-A Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-12-05 US disclosed