Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859554 | 0.82 | TSHR (0.48) | TSHRTHRBALDH1A1KDM4ELMNA | |
| SCHEMBL3012356 | 0.80 | TSHR (0.43) | TSHRTHRBALDH1A1KDM4ELMNA | |
| SCHEMBL4675894 | 0.80 | TSHR (0.43) | TSHRTHRBALDH1A1KDM4ELMNA | |
| Ammonia Solution, Strong SCHEMBL27753009 | 0.78 | TSHR (0.42) | TSHRTHRBALDH1A1KDM4ELMNA | |
| SCHEMBL8185907 | 0.78 | — | — | |
| SCHEMBL8188882 | 0.78 | — | — | |
| SCHEMBL8970752 | 0.76 | — | — | |
| SCHEMBL27357 | 0.76 | THRB (0.63) | TSHRTHRBALDH1A1KDM4ELMNA | |
| SCHEMBL860176 | 0.76 | TSHR (0.41) | TSHRTHRBALDH1A1KDM4ELMNA | |
| SCHEMBL21796075 | 0.76 | TSHR (0.41) | TSHRTHRBALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521145-A | Iminothiazoline derivatives and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0683160-A1 | Iminothiazoline derivatives and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-11-22 | — | — | EP | disclosed |