Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417120 | 0.83 | HTT (0.47) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL3844555 | 0.82 | LMNA (0.58) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL1440479 | 0.80 | LMNA (0.56) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL4425132 | 0.80 | HSD17B10 (0.50) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL1439677 | 0.79 | LMNA (0.57) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL734006 | 0.79 | L3MBTL1 (0.57) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL736556 | 0.79 | L3MBTL1 (0.57) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL734005 | 0.79 | L3MBTL1 (0.57) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL18667208 | 0.78 | LMNA (0.60) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 | |
| SCHEMBL18667866 | 0.78 | LMNA (0.60) | LMNASMN1; SMN2SLC1A3SLC1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567840-A | AS 4-AMINOBUTYRIC ACID AGONIST; MUSCLE RELAXANTS | CIBA-GEIGY CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| US-5461040-A | Therapy of spinal spacticity, multiple sclerosis, cerebral palsy, trigeminus neuralgia, drug withdrawal, pain | CIBA-GEIGY CORPORATION (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0399949-B1 | Substituted aminoalkylphosphinic acids | CIBA GEIGY AG (CH) | 1995-04-12 | — | — | EP | disclosed |
| US-5281747-A | Pharmaceuticals | CIBA-GEIGY CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0399949-A1 | Substituted aminoalkylphosphinic acids | CIBA-GEIGY AG (CH) | 1990-11-28 | — | — | EP | disclosed |