Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970913 | 0.83 | LMNA (0.51) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL3844555 | 0.78 | LMNA (0.58) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL10929167 | 0.78 | HTT (0.46) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL9336275 | 0.77 | HTT (0.59) | HTTLMNASMN1; SMN2TGM2L3MBTL1 | |
| SCHEMBL13725441 | 0.77 | HTT (0.59) | HTTLMNASMN1; SMN2TGM2L3MBTL1 | |
| SCHEMBL1439677 | 0.77 | LMNA (0.57) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL9416993 | 0.77 | CETP (0.59) | HTTLMNASMN1; SMN2TGM2L3MBTL1 | |
| SCHEMBL13853971 | 0.76 | HTT (0.58) | HTTLMNASMN1; SMN2TGM2L3MBTL1 | |
| SCHEMBL1667805 | 0.76 | HTT (0.72) | HTTLMNASMN1; SMN2TGM2CTSL | |
| SCHEMBL1442202 | 0.76 | LMNA (0.56) | HTTLMNASMN1; SMN2TGM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300679-A | Antagonists to 4-aminobutyric acid | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-5190933-A | Treatment of cognitive and memory disorders | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5064819-A | Antidepressants, anxiolytic agents, GABA antagonists | CIBA-GEIGY CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| US-5051524-A | Treatment of a phosphinic acid with an anhydrous protic medium | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |
| US-5013863-A | Learning enhancement | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |