Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970956 | 0.85 | MEN1 (0.46) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8854355 | 0.82 | ALDH1A1 (0.55) | TSHRALDH1A1SMN1; SMN2HSD11B1MEN1 | |
| SCHEMBL8972029 | 0.79 | ALDH1A1 (0.47) | TSHRALDH1A1SMN1; SMN2HSD11B1MEN1 | |
| SCHEMBL8971748 | 0.77 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2HSD11B1MEN1 | |
| SCHEMBL29625364 | 0.75 | TSHR (0.72) | TSHRALDH1A1SMN1; SMN2HSD11B1MEN1 | |
| SCHEMBL8971864 | 0.74 | HTT (0.43) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8971533 | 0.74 | TSHR (0.64) | TSHRALDH1A1SMN1; SMN2HSD11B1MEN1 | |
| SCHEMBL8854362 | 0.74 | MEN1 (0.44) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8971289 | 0.74 | MEN1 (0.51) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8971548 | 0.72 | TSHR (0.41) | TSHRALDH1A1SMN1; SMN2HSD11B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521260-A | ALKENYLNADIMIDE, VINYL COMPOUND, PHENOLIC RESIN | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |