SCHEMBL8971109

SCHEMBL8971109

Fc1ncnc(Cl)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83499 0.78
SCHEMBL83934 0.73
SCHEMBL22863895 0.69 ALDH1A1 (0.38)
SCHEMBL3706204 0.69
SCHEMBL6719860 0.67 PDE4A (0.31)
SCHEMBL2424060 0.67 CA2 (0.31)
SCHEMBL31542578 0.67
SCHEMBL2120002 0.67
SCHEMBL1440581 0.67
SCHEMBL83611 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7082500-A None JP disclosed
US-5498700-A Naphthylazonaphthol dyes which contain a 5-chloro-6-fluoropyrimidin-4-yl reactive group BAYER AKTIENGESELLSCHAFT (DE) 1996-03-12 US disclosed
JP-H0782500-A REACTIVE DYE BAYER AG 1995-03-28 JP disclosed
EP-0641840-A1 Reactive dyes BAYER AG (DE) 1995-03-08 EP disclosed
EP-0377189-B1 Reactive dyes BAYER AG (DE) 1994-09-07 EP disclosed
US-5241056-A REACTIVE MONOAZO DYESTUFFS WHICH CONTAIN ALKYLBENZENE AND CHLOROFLUORO PYRIMIDINE SUBSTITUENTS BAYER AKTIENGESELLSCHAFT (DE) 1993-08-31 US disclosed
EP-0513617-A1 Reactive dyes BAYER AG (DE) 1992-11-19 EP disclosed
US-5093482-A REACTIVE DYESTUFFS BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed