Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | KLF10 | Q13118 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055188 | 0.85 | NOS2 (0.75) | NOS2SLC6A4SLC6A2CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL9293022 | 0.84 | NOS2 (0.73) | NOS2SLC6A4SLC6A2CYP2D6CYP1A2 | |
| SCHEMBL7055269 | 0.83 | SLC6A2 (0.58) | NOS2SLC6A4SLC6A2CYP2D6CYP1A2 | |
| SCHEMBL7050739 | 0.82 | SLC6A4 (0.62) | NOS2SLC6A4SLC6A2CYP2D6CYP1A2 | |
| SCHEMBL8971047 | 0.82 | SLC6A4 (0.76) | NOS2SLC6A4SLC6A2CYP2D6CYP1A2 | |
| SCHEMBL8971814 | 0.82 | SLC6A2 (0.76) | NOS2SLC6A4SLC6A2CYP2D6CYP1A2 | |
| SCHEMBL9293360 | 0.81 | SLC6A9 (0.53) | NOS2SLC6A4SLC6A2CYP2D6CYP1A2 | |
| SCHEMBL8971677 | 0.79 | SLC6A4 (0.70) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8971176 | 0.78 | SLC6A2 (0.48) | NOS2SLC6A4SLC6A2CYP2D6CYP1A2 | |
| Succinic Acid SCHEMBL9411483 | 0.77 | NOS2 (0.64) | NOS2SLC6A4SLC6A2CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545425-B1 | 2-(3-Phenylpropyl)hydrazines, intermediates in and a process for the preparation thereof, and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-03-20 | — | — | EP | disclosed |
| US-5268468-A | Or optical isomers thereof | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-12-07 | — | — | US | disclosed |
| US-5229417-A | Obsessive compulsive disorders | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | disclosed |
| EP-0545425-A1 | 2-(3-Phenylpropyl)hydrazines, intermediates in and a process for the preparation thereof, and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-06-09 | — | — | EP | disclosed |