SCHEMBL8971281

SCHEMBL8971281

CCCCCCCC1CCC(C(=O)Oc2ccc(-c3ccc(-c4ccc(OCC)c(F)c4F)cc3)cc2F)OC1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.32
NAAA Q02083 1/20 0.32
RARB P10826 4/20 0.32
RARA P10276 2/20 0.32
RARG P13631 1/20 0.32
MGLL Q99685 3/20 0.32
PTPN11 Q06124 1/20 0.31
GRIN1 Q05586 2/20 0.31
GRIN2B Q13224 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8971126 0.93 FFAR4 (0.33) FFAR4GRIN1GRIN2B
SCHEMBL8970995 0.93 FFAR4 (0.33) FFAR4GRIN1GRIN2B
SCHEMBL12999672 0.90 RARB (0.31) RARBRARARARGMGLL
SCHEMBL8970987 0.89 RARB (0.34) FFAR4RARBPTPN11
SCHEMBL8971115 0.84 PTPN11 (0.38) FFAR4RARBRARARARGMGLL
SCHEMBL12999685 0.84 THRA (0.30)
SCHEMBL13000851 0.84 NAAA (0.34) FFAR4NAAAMGLLGRIN1GRIN2B
SCHEMBL8941060 0.83 GRIN1 (0.33) NAAAMGLLPTPN11GRIN1GRIN2B
SCHEMBL8971500 0.82 FFAR4 (0.34) FFAR4NAAARARBRARARARG
SCHEMBL8971485 0.82 RARB (0.37) FFAR4NAAARARBRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed