Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 5/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971126 | 0.91 | FFAR4 (0.33) | FFAR4 | |
| SCHEMBL8970995 | 0.91 | FFAR4 (0.33) | FFAR4 | |
| SCHEMBL8971281 | 0.89 | FFAR4 (0.32) | RARBFFAR4PTPN11 | |
| SCHEMBL8971017 | 0.85 | PPARD (0.35) | RARBFAAHPTGS2FFAR4PTPN11 | |
| SCHEMBL8970464 | 0.84 | FFAR4 (0.33) | RARBFFAR4ESR1PTPN11FFAR1 | |
| SCHEMBL12999685 | 0.81 | THRA (0.30) | — | |
| SCHEMBL8971199 | 0.81 | RARB (0.40) | RARBFFAR4PTPN11 | |
| SCHEMBL8971724 | 0.81 | GRM2 (0.33) | ESR1 | |
| SCHEMBL8939896 | 0.81 | KDM1A (0.35) | RARBESR1 | |
| SCHEMBL8971819 | 0.80 | RARB (0.37) | RARBFAAHPTPN11S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |