Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971618 | 0.86 | RARB (0.38) | PPARDRARBTHRATHRBPTPN11 | |
| SCHEMBL8971327 | 0.86 | PTPN11 (0.36) | THRATHRBPTPN11HDAC6PLA2G2D | |
| SCHEMBL8971199 | 0.84 | RARB (0.40) | PPARDRARBTHRATHRBPTPN11 | |
| SCHEMBL8971632 | 0.83 | RARB (0.43) | PPARDRARBTHRATHRBPTPN11 | |
| SCHEMBL8971017 | 0.82 | PPARD (0.35) | PPARDRARBPTPN11S1PR1S1PR3 | |
| SCHEMBL8971099 | 0.82 | RARB (0.33) | PPARDRARBPTPN11S1PR1S1PR3 | |
| SCHEMBL8948466 | 0.82 | FPR2 (0.33) | PPARDRARBS1PR1S1PR3 | |
| SCHEMBL8948506 | 0.81 | FPR2 (0.33) | PPARDRARBPTPN11 | |
| SCHEMBL8972099 | 0.81 | PPARD (0.37) | PPARDPPARGPPARA | |
| SCHEMBL8970738 | 0.80 | S1PR1 (0.34) | PPARDRARBTHRATHRBPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |