Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.38 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971756 | 0.89 | PTPN11 (0.36) | THRATHRBPTPN11PLA2G2D | |
| SCHEMBL8971747 | 0.89 | PTPN11 (0.36) | THRATHRBPTPN11PLA2G2D | |
| SCHEMBL8971564 | 0.88 | PTPN11 (0.39) | RARBPPARDTHRATHRBPTPN11 | |
| SCHEMBL8971484 | 0.83 | PPARD (0.40) | RARBPPARDTHRATHRBPTPN11 | |
| SCHEMBL8970864 | 0.83 | RARB (0.37) | RARBPPARDPTPN11 | |
| SCHEMBL8971819 | 0.82 | RARB (0.37) | RARBPPARDTHRATHRBPTPN11 | |
| SCHEMBL8953695 | 0.82 | FPR2 (0.36) | RARBPPARDTHRATHRBPTPN11 | |
| SCHEMBL8953724 | 0.82 | FPR2 (0.36) | RARBPPARDTHRATHRBPTPN11 | |
| SCHEMBL8953720 | 0.82 | FPR2 (0.36) | RARBPPARDTHRATHRBPTPN11 | |
| SCHEMBL8953332 | 0.82 | FPR2 (0.36) | RARBPPARDTHRATHRBPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |