Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RARG | P13631 | 3/20 | 0.40 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NEU3 | Q9UQ49 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971916 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2POLBMAPTKDM4EGAA | |
| SCHEMBL10358736 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2RARGRARBMAPTKDM4E | |
| SCHEMBL8971383 | 0.81 | NEU3 (0.53) | SMN1; SMN2MAPTKDM4ENEU3MEN1 | |
| SCHEMBL8971776 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2RARGRARBPOLBCA1 | |
| SCHEMBL8971653 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBMAPTKDM4EL3MBTL1 | |
| SCHEMBL3278783 | 0.70 | CA12 (0.59) | SMN1; SMN2POLBMAPTCA1CA2 | |
| SCHEMBL16675402 | 0.67 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBMAPTPKMKMT2A | |
| SCHEMBL8971379 | 0.67 | CDC25B (0.40) | SMN1; SMN2RARGRARBMAPTKDM4E | |
| SCHEMBL1814868 | 0.66 | SMN1; SMN2 (0.61) | SMN1; SMN2POLBMAPTGAAL3MBTL1 | |
| SCHEMBL8971390 | 0.66 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBMAPTCA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527824-A | ADMINISTERING IN THE TREATMENT OF ASTHMA, PSORIASIS AND ALLERGIC CONDITIONS | RIKER LABORATORIES, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| US-5498745-A | ANTIALLERGEN INTERMEDIATES, INHIBITORS OF LEUKOTRIENES, LIPOXYGENASE INHIBITORS | RIKER LABORATORIES, INC. (US) | 1996-03-12 | — | — | US | disclosed |
| US-5495043-A | ANTIALLERGENS | RIKER LABORATORIES, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5416113-A | Bronchodilators | RIKER LABORATORIES, INC. (US) | 1995-05-16 | — | — | US | disclosed |
| US-5347036-A | Antiallergens | RIKER LABORATORIES, INC. (US) | 1994-09-13 | — | — | US | disclosed |
| US-5237070-A | Antiallergens, inhibiting bronchoconstriction | RIKER LABORATORIES, INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0212848-B1 | SUBSTITUTED-DI-T-BUTYLPHENOLS | RIKER LABORATORIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0212848-A2 | Substituted-di-t-butylphenols | RIKER LABORATORIES, INC. (US) | 1987-03-04 | — | — | EP | disclosed |