Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 5/20 | 0.37 |
| ▸ | MPI | P34949 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675402 | 0.90 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBGPR55ALDH1A1MAPT | |
| SCHEMBL2814567 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBGPR55ALDH1A1MAPT | |
| SCHEMBL8971776 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBALDH1A1KMT2ANPC1 | |
| SCHEMBL8971390 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBGPR55ALDH1A1MAPT | |
| SCHEMBL8971653 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBALDH1A1MAPTKMT2A | |
| SCHEMBL9490926 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2POLBALDH1A1MAPTMPI | |
| SCHEMBL10364440 | 0.79 | MAPT (0.55) | SMN1; SMN2ALDH1A1MAPTPKMKMT2A | |
| SCHEMBL14253718 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBGPR55ATMKMT2A | |
| SCHEMBL8971203 | 0.76 | RXRA (0.45) | SMN1; SMN2ALDH1A1NPSR1LMNAL3MBTL1 | |
| SCHEMBL8971980 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113625-A1 | Composition and method for inhibiting polymerization and polymer growth | UNIROYAL CHEMICAL COMPANY, INC. | 2005-05-26 | — | — | US | claimed |
| US-7943809-B2 | Composition and method for inhibiting polymerization and polymer growth | CHEMTURA CORPORATION (US) | 2011-05-17 | — | — | US | disclosed |
| EP-1235885-B1 | COMPOSITION AND METHOD FOR INHIBITING POLYMERIZATION AND POLYMER GROWTH | UNIROYAL CHEM CO INC (US) | 2007-08-15 | — | — | EP | disclosed |
| US-20050113626-A1 | Composition and method for inhibiting polymerization and polymer growth | UNIROYAL CHEMICAL COMPANY, INC., A CORPORATION OF THE STATE OF DELAWARE | 2005-05-26 | — | — | US | disclosed |
| US-20050113625-A1 | Composition and method for inhibiting polymerization and polymer growth | UNIROYAL CHEMICAL COMPANY, INC. | 2005-05-26 | — | — | US | disclosed |
| US-5258281-A | Light sensitive silver halide multilayer elements with dyes and heat development accelerators | CANON KABUSHIKI KAISHA (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0486246-A1 | Heat-developable photosensitive material | CANON KABUSHIKI KAISHA (JP) | 1992-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113625-A1 | Composition and method for inhibiting polymerization and polymer growth | ELL, ELOVL1, ELOVL5 | SMN1; SMN2 417/4885POLB 108/4885GPR55 3709/4885 |
| US-20050113626-A1 | Composition and method for inhibiting polymerization and polymer growth | ELL, ELOVL1, ELOVL5 | SMN1; SMN2 417/4885POLB 108/4885GPR55 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.