Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 4/20 | 0.38 |
| ▸ | RXRB | P28702 | 4/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675402 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1NPC1POLBKMT2A | |
| SCHEMBL8971653 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MAOBRXRARXRB | |
| SCHEMBL1814868 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1MEN1NPC1POLB | |
| SCHEMBL2814567 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1NPC1POLBKMT2A | |
| SCHEMBL8971916 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1RXRARXRBRXRG | |
| SCHEMBL8971980 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2CA1CA2ALDH1A1CA12 | |
| SCHEMBL8971498 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2CA1CA2SRD5A2CA12 | |
| SCHEMBL8971203 | 0.79 | RXRA (0.45) | SMN1; SMN2CA1CA2ALDH1A1RXRA | |
| SCHEMBL10364440 | 0.78 | MAPT (0.55) | SMN1; SMN2ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL10358736 | 0.77 | SMN1; SMN2 (0.60) | SMN1; SMN2SRD5A2ALDH1A1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7053485-A | — | — | None | — | — | JP | disclosed |
| US-5527824-A | ADMINISTERING IN THE TREATMENT OF ASTHMA, PSORIASIS AND ALLERGIC CONDITIONS | RIKER LABORATORIES, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| US-5498745-A | ANTIALLERGEN INTERMEDIATES, INHIBITORS OF LEUKOTRIENES, LIPOXYGENASE INHIBITORS | RIKER LABORATORIES, INC. (US) | 1996-03-12 | — | — | US | disclosed |
| US-5495043-A | ANTIALLERGENS | RIKER LABORATORIES, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5416113-A | Bronchodilators | RIKER LABORATORIES, INC. (US) | 1995-05-16 | — | — | US | disclosed |
| JP-H0753485-A | SUBSTITUTED DI-T-BUTYLCYCLOHEXADIENONE | RIKER LAB INC | 1995-02-28 | — | — | JP | disclosed |
| US-5347036-A | Antiallergens | RIKER LABORATORIES, INC. (US) | 1994-09-13 | — | — | US | disclosed |
| US-5237070-A | Antiallergens, inhibiting bronchoconstriction | RIKER LABORATORIES, INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0212848-B1 | SUBSTITUTED-DI-T-BUTYLPHENOLS | RIKER LABORATORIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0212848-A2 | Substituted-di-t-butylphenols | RIKER LABORATORIES, INC. (US) | 1987-03-04 | — | — | EP | disclosed |