Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31151392 | 1.00 | LMNA (0.65) | LMNAKDM4EGLAMAPTHTT | |
| SCHEMBL27462399 | 0.79 | LMNA (0.83) | LMNAKDM4EGLAMAPTHTT | |
| Clopamide SCHEMBL124598 | 0.79 | KDM4E (1.00) | LMNAKDM4EGLAMAPTHTT | |
| Clopamide SCHEMBL1650071 | 0.79 | KDM4E (1.00) | LMNAKDM4EGLAMAPTHTT | |
| SCHEMBL8971757 | 0.73 | CA1 (0.52) | LMNAKDM4EGLAMAPTHTT | |
| SCHEMBL21962924 | 0.69 | CA2 (0.61) | KDM4EGLAMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL10743411 | 0.68 | CA1 (0.56) | KDM4EMAPTHSD17B10PTPN1SMN1; SMN2 | |
| SCHEMBL11024029 | 0.68 | CA1 (0.46) | LMNAKDM4EMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL11929010 | 0.66 | LMNA (0.60) | LMNAKDM4EGLAMAPTHTT | |
| SCHEMBL3456234 | 0.65 | SMN1; SMN2 (0.55) | HTTACHEKMT2ASMN1; SMN2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510489-A | Method of preparing 1-amino-2, 6-dimethylpiperidine | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |