SCHEMBL8971886

SCHEMBL8971886

C=Cc1ccc(C(N)=O)cc1.CN(C)CC(O)COc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.50
ABCB1 P08183 5/20 0.48
PARP10 Q53GL7 2/20 0.47
HTT P42858 1/20 0.44
CDK4 P11802 2/20 0.44
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.43
HPGD P15428 1/20 0.43
CDK2 P24941 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzamide SCHEMBL4775810 0.89 HIF1A (0.58) HIF1AABCB1PARP10HTTCDK4
SCHEMBL5823658 0.84 ALDH1A1 (0.64) HIF1AABCB1PARP10HTTCDK4
SCHEMBL5821382 0.82 KMT2A (0.61) HIF1AABCB1PARP10CDK4ALDH1A1
SCHEMBL258823 0.79 HIF1A (0.75) HIF1AABCB1HTTCDK4ALDH1A1
SCHEMBL9448527 0.78 HIF1A (0.69) HIF1AABCB1PARP10HTTALDH1A1
SCHEMBL6552266 0.77 ABCB1 (0.76) HIF1AABCB1HTTCDK4ALDH1A1
Hydrochloric Acid SCHEMBL22228312 0.76 ABCB1 (0.74) HIF1AABCB1HTTCDK4ALDH1A1
Chloromethane SCHEMBL8216574 0.75 ABCB1 (0.72) HIF1AABCB1HTTCDK4ALDH1A1
SCHEMBL9812016 0.74 ABCB1 (0.54) ABCB1PARP10ALDH1A1LMNA
SCHEMBL9812027 0.74 ABCB1 (0.54) ABCB1PARP10ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544933-B1 A pressure sensitive adhesive composition and a pressure sensitive adhesive sheet, a label and a laminate utilizing it LINTEC CORP (JP) 1996-02-07 EP disclosed
US-5389437-A Paper or synthetic resin film coated with adhesive having improved blister resistance, removability, cohesive strength, heat resistance, corrosion resistance SAIDEN CHEMICAL INDUSTRY CO., LTD. (JP) 1995-02-14 US disclosed
US-5278271-A Acrylic copolymer comprising aminoalkyl (meth)acrylamide SAIDEN CHEMICAL INDUSTRY CO., LTD. (JP) 1994-01-11 US disclosed
EP-0544933-A1 A pressure sensitive adhesive composition and a pressure sensitive adhesive sheet, a label and a laminate utilizing it LINTEC Corporation (JP) 1993-06-09 EP disclosed