Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 7/20 | 0.43 |
| ▸ | CTSD | P07339 | 6/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 4/20 | 0.39 |
| ▸ | FPR2 | P25090 | 4/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CPA2 | P48052 | 1/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25465168 | 1.00 | ALDH1A1 (0.45) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL2162504 | 0.99 | CTSD (0.45) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL18328807 | 0.99 | CTSD (0.45) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL23133173 | 0.99 | CTSD (0.45) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL6041187 | 0.99 | CTSD (0.45) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL24178172 | 0.96 | CTSD (0.48) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL25466117 | 0.92 | FOLH1 (0.49) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL24427098 | 0.89 | CTSD (0.40) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL25466074 | 0.87 | BACE1 (0.39) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL25465185 | 0.86 | REN (0.52) | BACE1CTSDCTSBFPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543310-B1 | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5395824-A | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LIMITED (JP) | 1995-03-07 | — | — | US | disclosed |