Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971952 | 0.92 | PLA2G2D (0.32) | S1PR1PTPN11 | |
| SCHEMBL8971848 | 0.88 | GRM2 (0.35) | S1PR1S1PR3PPARD | |
| SCHEMBL8970534 | 0.86 | S1PR1 (0.34) | S1PR1FPR2PTPN11S1PR4S1PR3 | |
| SCHEMBL8971880 | 0.85 | S1PR1 (0.33) | S1PR1FPR2PTPN11S1PR4S1PR3 | |
| SCHEMBL8971605 | 0.83 | NAAA (0.31) | — | |
| SCHEMBL8950130 | 0.83 | FPR2 (0.35) | S1PR1FPR2PTPN11 | |
| SCHEMBL8950136 | 0.83 | PTPN11 (0.34) | S1PR1FPR2PTPN11S1PR4S1PR3 | |
| SCHEMBL8950464 | 0.83 | PTPN11 (0.34) | S1PR1FPR2PTPN11S1PR4S1PR3 | |
| SCHEMBL8950395 | 0.83 | PTPN11 (0.34) | S1PR1FPR2PTPN11S1PR4S1PR3 | |
| SCHEMBL8950448 | 0.83 | PTPN11 (0.34) | S1PR1FPR2PTPN11S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |