Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971952 | 0.88 | PLA2G2D (0.32) | S1PR1 | |
| SCHEMBL8971936 | 0.88 | S1PR1 (0.33) | PPARDS1PR1S1PR3 | |
| SCHEMBL8971724 | 0.84 | GRM2 (0.33) | GRM2 | |
| SCHEMBL8970738 | 0.84 | S1PR1 (0.34) | PPARDS1PR1S1PR3FFAR1FFAR4 | |
| SCHEMBL8972128 | 0.84 | PPARD (0.34) | GRM2PPARDS1PR1S1PR3FFAR1 | |
| SCHEMBL8948466 | 0.82 | FPR2 (0.33) | PPARDS1PR1S1PR3 | |
| SCHEMBL8948506 | 0.81 | FPR2 (0.33) | PPARD | |
| SCHEMBL8972099 | 0.81 | PPARD (0.37) | PPARD | |
| SCHEMBL8971017 | 0.81 | PPARD (0.35) | PPARDS1PR1S1PR3FFAR1FFAR4 | |
| SCHEMBL14226815 | 0.81 | GRM2 (0.32) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |