Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PHPT1 | Q9NRX4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350967 | 0.75 | CA1 (0.40) | CA1CA2CA9MAPTPOLB | |
| SCHEMBL8971050 | 0.74 | PGK1 (0.39) | CA1CA2CA9MAPTPOLB | |
| SCHEMBL1134926 | 0.71 | CA1 (0.53) | CA1CA2CA9MAPTPOLB | |
| SCHEMBL29501816 | 0.71 | CA1 (0.53) | CA1CA2CA9MAPTPOLB | |
| SCHEMBL8971443 | 0.70 | PGK1 (0.40) | CA1CA2CA9MAPTPOLB | |
| SCHEMBL18750435 | 0.69 | CA1 (0.56) | CA1CA2CA9MAPTPOLB | |
| SCHEMBL8488270 | 0.66 | CA1 (0.44) | CA1CA2CA9MAPTPOLB | |
| SCHEMBL26961906 | 0.65 | CA1 (0.49) | CA1CA2CA9MAPTPOLB | |
| SCHEMBL16769416 | 0.64 | CA1 (0.45) | CA1CA2CA9MAPTPOLB | |
| SCHEMBL3298778 | 0.64 | SMN1; SMN2 (0.54) | CA1CA2CA9MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |