Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971050 | 0.92 | PGK1 (0.39) | PGK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL8970733 | 0.83 | AGER (0.43) | PGK1ALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL8971117 | 0.76 | AGER (0.47) | ALDH1A1KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL11797206 | 0.75 | CA1 (0.53) | PGK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL7076639 | 0.73 | CA1 (0.51) | PGK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL9814177 | 0.73 | POLB (0.53) | PGK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL7360659 | 0.72 | AGER (0.40) | PGK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL7360982 | 0.71 | PGK1 (0.39) | PGK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL10616893 | 0.71 | PGK1 (0.53) | PGK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL10242037 | 0.71 | CA1 (0.49) | PGK1CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |