Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971443 | 0.92 | PGK1 (0.40) | PGK1CA1CA2CA9KDM4E | |
| SCHEMBL8971117 | 0.84 | AGER (0.47) | KDM4EKMT2APOLBMEN1LMNA | |
| SCHEMBL7360659 | 0.78 | AGER (0.40) | PGK1CA1CA2CA9KDM4E | |
| SCHEMBL8970918 | 0.76 | MTNR1B (0.43) | KDM4EKMT2APOLBMEN1LMNA | |
| SCHEMBL8970733 | 0.75 | AGER (0.43) | PGK1KDM4EKMT2APOLBMEN1 | |
| SCHEMBL7360982 | 0.75 | PGK1 (0.39) | PGK1CA1CA2CA9KDM4E | |
| SCHEMBL8971982 | 0.74 | SMN1; SMN2 (0.41) | KDM4EKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8971990 | 0.74 | CA1 (0.39) | CA1CA2CA9KDM4EKMT2A | |
| SCHEMBL8971536 | 0.73 | MGAT2 (0.44) | KDM4EKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8971265 | 0.73 | SMN1; SMN2 (0.42) | CA1CA2KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |