Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1580097 | 0.89 | TDP1 (0.51) | MEN1KMT2AMAOBTDP1L3MBTL1 | |
| SCHEMBL6210465 | 0.84 | KMT2A (0.50) | MEN1KMT2ARAB9ACASP3SMN1; SMN2 | |
| SCHEMBL6210467 | 0.84 | KMT2A (0.50) | MEN1KMT2ARAB9ACASP3SMN1; SMN2 | |
| SCHEMBL17892090 | 0.82 | GLS (0.44) | MEN1KMT2ARAB9ACASP3SMN1; SMN2 | |
| SCHEMBL17892087 | 0.82 | GLS (0.44) | MEN1KMT2ARAB9ACASP3SMN1; SMN2 | |
| SCHEMBL23020626 | 0.81 | NPC1 (0.47) | MEN1KMT2ARAB9ACASP3SMN1; SMN2 | |
| SCHEMBL22121427 | 0.80 | GLS (0.59) | RAB9ACASP3SMN1; SMN2NPC1SENP8 | |
| SCHEMBL17419395 | 0.78 | GPR84 (0.48) | MEN1KMT2ARAB9ACASP3SMN1; SMN2 | |
| SCHEMBL15955946 | 0.78 | GPR84 (0.48) | MEN1KMT2ARAB9ACASP3SMN1; SMN2 | |
| SCHEMBL5680357 | 0.77 | ACHE (0.48) | MEN1KMT2AALDH1A1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596802-B1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1996-03-20 | — | — | EP | disclosed |
| EP-0596802-A1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1994-05-11 | — | — | EP | disclosed |